diff --git a/.github/workflows/release.yml b/.github/workflows/release.yml
index a83ff6b..720d509 100644
--- a/.github/workflows/release.yml
+++ b/.github/workflows/release.yml
@@ -50,7 +50,7 @@ jobs:
       - name: Configure workflow
         id: config
         run: |
-          pip install ci-helper cython
+          pip install ci-helper
 
           # Load repo-specific variables and overrides:
           VARS_FILE=".github/workflows/release-vars.sh"
diff --git a/pyproject.toml b/pyproject.toml
index 1a8e571..2c443bd 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -1,5 +1,5 @@
 [build-system]
-requires = ["setuptools>=64", "setuptools_scm>=8", "cython",
+requires = ["setuptools>=74.1.0", "setuptools_scm>=8", "cython",
             "numpy>=2.0,<3; python_version>'3.8'"]
 build-backend = "setuptools.build_meta"
 
@@ -10,6 +10,9 @@ local_scheme = "no-local-version"
 [tool.setuptools]
 zip-safe = false
 include-package-data = true
+ext-modules = [
+    {name = "labscript_c_extensions.runviewer.resample", sources = ["src/runviewer/resample.pyx"]}
+]
 
 [tool.setuptools.packages]
 find = {namespaces = false}
diff --git a/setup.py b/setup.py
deleted file mode 100644
index e0f6c99..0000000
--- a/setup.py
+++ /dev/null
@@ -1,19 +0,0 @@
-import os
-from setuptools import setup
-from setuptools.extension import Extension
-from Cython.Distutils import build_ext
-
-
-CMDCLASS = {"build_ext": build_ext}
-
-EXT_MODULES = [
-    Extension(
-        "labscript_c_extensions.runviewer.resample",
-        sources=[os.path.join("src", "runviewer", "resample.pyx")],
-    )
-]
-
-setup(
-    cmdclass=CMDCLASS,
-    ext_modules=EXT_MODULES,
-)