diff --git a/CHANGELOG.md b/CHANGELOG.md
index 117ac56a40..dbfb633f8d 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -6,6 +6,23 @@
 > make sure you follow our [migration guide](https://docs.sentry.io/platforms/react-native/migration/) first.
 <!-- prettier-ignore-end -->
 
+## Unreleased
+
+### Features
+
+- Add experimental `sentry-span-attributes` prop to attach custom attributes to user interaction spans ([#5569](https://github.com/getsentry/sentry-react-native/pull/5569))
+  ```tsx
+  <Pressable
+    sentry-label="checkout"
+    sentry-span-attributes={{
+      'user.type': 'premium',
+      'cart.value': 150
+    }}
+    onPress={handleCheckout}>
+    <Text>Checkout</Text>
+  </Pressable>
+  ```
+
 ## 7.10.0
 
 ### Fixes
diff --git a/packages/core/src/js/touchevents.tsx b/packages/core/src/js/touchevents.tsx
index c6eb78770c..907790e262 100644
--- a/packages/core/src/js/touchevents.tsx
+++ b/packages/core/src/js/touchevents.tsx
@@ -1,4 +1,4 @@
-import type { SeverityLevel } from '@sentry/core';
+import type { SeverityLevel, SpanAttributeValue } from '@sentry/core';
 import { addBreadcrumb, debug, dropUndefinedKeys, getClient, SEMANTIC_ATTRIBUTE_SENTRY_ORIGIN } from '@sentry/core';
 import * as React from 'react';
 import type { GestureResponderEvent } from 'react-native';
@@ -39,6 +39,13 @@ export type TouchEventBoundaryProps = {
    * Label Name used to identify the touched element.
    */
   labelName?: string;
+  /**
+   * Custom attributes to add to user interaction spans.
+   * Accepts an object with string keys and values that are strings, numbers, booleans, or arrays.
+   *
+   * @experimental This API is experimental and may change in future releases.
+   */
+  spanAttributes?: Record<string, SpanAttributeValue>;
 };
 
 const touchEventStyles = StyleSheet.create({
@@ -52,6 +59,7 @@ const DEFAULT_BREADCRUMB_TYPE = 'user';
 const DEFAULT_MAX_COMPONENT_TREE_SIZE = 20;
 
 const SENTRY_LABEL_PROP_KEY = 'sentry-label';
+const SENTRY_SPAN_ATTRIBUTES_PROP_KEY = 'sentry-span-attributes';
 const SENTRY_COMPONENT_PROP_KEY = 'data-sentry-component';
 const SENTRY_ELEMENT_PROP_KEY = 'data-sentry-element';
 const SENTRY_FILE_PROP_KEY = 'data-sentry-source-file';
@@ -204,6 +212,28 @@ class TouchEventBoundary extends React.Component<TouchEventBoundaryProps> {
     });
     if (span) {
       span.setAttribute(SEMANTIC_ATTRIBUTE_SENTRY_ORIGIN, SPAN_ORIGIN_AUTO_INTERACTION);
+
+      // Apply custom attributes from sentry-span-attributes prop
+      // Traverse the component tree to find custom attributes
+      let instForAttributes: ElementInstance | undefined = e._targetInst;
+      let customAttributes: Record<string, SpanAttributeValue> | undefined;
+
+      while (instForAttributes) {
+        if (instForAttributes.elementType?.displayName === TouchEventBoundary.displayName) {
+          break;
+        }
+
+        customAttributes = getSpanAttributes(instForAttributes);
+        if (customAttributes && Object.keys(customAttributes).length > 0) {
+          break;
+        }
+
+        instForAttributes = instForAttributes.return;
+      }
+
+      if (customAttributes && Object.keys(customAttributes).length > 0) {
+        span.setAttributes(customAttributes);
+      }
     }
   }
 
@@ -291,6 +321,26 @@ function getLabelValue(props: Record<string, unknown>, labelKey: string | undefi
       : undefined;
 }
 
+function getSpanAttributes(currentInst: ElementInstance): Record<string, SpanAttributeValue> | undefined {
+  if (!currentInst.memoizedProps) {
+    return undefined;
+  }
+
+  const props = currentInst.memoizedProps;
+  const attributes = props[SENTRY_SPAN_ATTRIBUTES_PROP_KEY];
+
+  // Validate that it's an object (not null, not array)
+  if (
+    typeof attributes === 'object' &&
+    attributes !== null &&
+    !Array.isArray(attributes)
+  ) {
+    return attributes as Record<string, SpanAttributeValue>;
+  }
+
+  return undefined;
+}
+
 /**
  * Convenience Higher-Order-Component for TouchEventBoundary
  * @param WrappedComponent any React Component
diff --git a/packages/core/test/touchevents.test.tsx b/packages/core/test/touchevents.test.tsx
index 11c62e64d3..32089530b8 100644
--- a/packages/core/test/touchevents.test.tsx
+++ b/packages/core/test/touchevents.test.tsx
@@ -4,6 +4,7 @@
 import type { SeverityLevel } from '@sentry/core';
 import * as core from '@sentry/core';
 import { TouchEventBoundary } from '../src/js/touchevents';
+import * as userInteractionModule from '../src/js/tracing/integrations/userInteraction';
 import { getDefaultTestClientOptions, TestClient } from './mocks/client';
 
 describe('TouchEventBoundary._onTouchStart', () => {
@@ -310,4 +311,243 @@ describe('TouchEventBoundary._onTouchStart', () => {
       type: defaultProps.breadcrumbType,
     });
   });
+
+  describe('sentry-span-attributes', () => {
+    it('sets custom attributes from prop on user interaction span', () => {
+      const { defaultProps } = TouchEventBoundary;
+      const boundary = new TouchEventBoundary(defaultProps);
+
+      const mockSpan = {
+        setAttribute: jest.fn(),
+        setAttributes: jest.fn(),
+      };
+      jest.spyOn(userInteractionModule, 'startUserInteractionSpan').mockReturnValue(mockSpan as any);
+
+      const event = {
+        _targetInst: {
+          elementType: { displayName: 'Button' },
+          memoizedProps: {
+            'sentry-label': 'checkout',
+            'sentry-span-attributes': {
+              'user.subscription': 'premium',
+              'cart.items': '3',
+              'feature.enabled': true,
+            },
+          },
+        },
+      };
+
+      // @ts-expect-error Calling private member
+      boundary._onTouchStart(event);
+
+      expect(mockSpan.setAttributes).toHaveBeenCalledWith({
+        'user.subscription': 'premium',
+        'cart.items': '3',
+        'feature.enabled': true,
+      });
+    });
+
+    it('handles multiple attribute types (string, number, boolean)', () => {
+      const { defaultProps } = TouchEventBoundary;
+      const boundary = new TouchEventBoundary(defaultProps);
+
+      const mockSpan = {
+        setAttribute: jest.fn(),
+        setAttributes: jest.fn(),
+      };
+      jest.spyOn(userInteractionModule, 'startUserInteractionSpan').mockReturnValue(mockSpan as any);
+
+      const event = {
+        _targetInst: {
+          elementType: { displayName: 'Button' },
+          memoizedProps: {
+            'sentry-label': 'test',
+            'sentry-span-attributes': {
+              'string.value': 'test',
+              'number.value': 42,
+              'boolean.value': false,
+              'array.value': ['a', 'b', 'c'],
+            },
+          },
+        },
+      };
+
+      // @ts-expect-error Calling private member
+      boundary._onTouchStart(event);
+
+      expect(mockSpan.setAttributes).toHaveBeenCalledWith({
+        'string.value': 'test',
+        'number.value': 42,
+        'boolean.value': false,
+        'array.value': ['a', 'b', 'c'],
+      });
+    });
+
+    it('handles invalid span attributes gracefully (null)', () => {
+      const { defaultProps } = TouchEventBoundary;
+      const boundary = new TouchEventBoundary(defaultProps);
+
+      const mockSpan = {
+        setAttribute: jest.fn(),
+        setAttributes: jest.fn(),
+      };
+      jest.spyOn(userInteractionModule, 'startUserInteractionSpan').mockReturnValue(mockSpan as any);
+
+      const event = {
+        _targetInst: {
+          elementType: { displayName: 'Button' },
+          memoizedProps: {
+            'sentry-label': 'test',
+            'sentry-span-attributes': null,
+          },
+        },
+      };
+
+      // @ts-expect-error Calling private member
+      boundary._onTouchStart(event);
+
+      expect(mockSpan.setAttributes).not.toHaveBeenCalled();
+    });
+
+    it('handles invalid span attributes gracefully (array)', () => {
+      const { defaultProps } = TouchEventBoundary;
+      const boundary = new TouchEventBoundary(defaultProps);
+
+      const mockSpan = {
+        setAttribute: jest.fn(),
+        setAttributes: jest.fn(),
+      };
+      jest.spyOn(userInteractionModule, 'startUserInteractionSpan').mockReturnValue(mockSpan as any);
+
+      const event = {
+        _targetInst: {
+          elementType: { displayName: 'Button' },
+          memoizedProps: {
+            'sentry-label': 'test',
+            'sentry-span-attributes': ['invalid', 'array'],
+          },
+        },
+      };
+
+      // @ts-expect-error Calling private member
+      boundary._onTouchStart(event);
+
+      expect(mockSpan.setAttributes).not.toHaveBeenCalled();
+    });
+
+    it('handles empty object gracefully', () => {
+      const { defaultProps } = TouchEventBoundary;
+      const boundary = new TouchEventBoundary(defaultProps);
+
+      const mockSpan = {
+        setAttribute: jest.fn(),
+        setAttributes: jest.fn(),
+      };
+      jest.spyOn(userInteractionModule, 'startUserInteractionSpan').mockReturnValue(mockSpan as any);
+
+      const event = {
+        _targetInst: {
+          elementType: { displayName: 'Button' },
+          memoizedProps: {
+            'sentry-label': 'test',
+            'sentry-span-attributes': {},
+          },
+        },
+      };
+
+      // @ts-expect-error Calling private member
+      boundary._onTouchStart(event);
+
+      expect(mockSpan.setAttributes).not.toHaveBeenCalled();
+    });
+
+    it('works with sentry-label', () => {
+      const { defaultProps } = TouchEventBoundary;
+      const boundary = new TouchEventBoundary(defaultProps);
+
+      const mockSpan = {
+        setAttribute: jest.fn(),
+        setAttributes: jest.fn(),
+      };
+      jest.spyOn(userInteractionModule, 'startUserInteractionSpan').mockReturnValue(mockSpan as any);
+
+      const event = {
+        _targetInst: {
+          elementType: { displayName: 'Button' },
+          memoizedProps: {
+            'sentry-label': 'checkout-button',
+            'sentry-span-attributes': {
+              'custom.key': 'value',
+            },
+          },
+        },
+      };
+
+      // @ts-expect-error Calling private member
+      boundary._onTouchStart(event);
+
+      expect(userInteractionModule.startUserInteractionSpan).toHaveBeenCalledWith({
+        elementId: 'checkout-button',
+        op: 'ui.action.touch',
+      });
+      expect(mockSpan.setAttributes).toHaveBeenCalledWith({
+        'custom.key': 'value',
+      });
+    });
+
+    it('finds attributes in component tree', () => {
+      const { defaultProps } = TouchEventBoundary;
+      const boundary = new TouchEventBoundary(defaultProps);
+
+      const mockSpan = {
+        setAttribute: jest.fn(),
+        setAttributes: jest.fn(),
+      };
+      jest.spyOn(userInteractionModule, 'startUserInteractionSpan').mockReturnValue(mockSpan as any);
+
+      const event = {
+        _targetInst: {
+          elementType: { displayName: 'Text' },
+          return: {
+            elementType: { displayName: 'Button' },
+            memoizedProps: {
+              'sentry-label': 'parent-button',
+              'sentry-span-attributes': {
+                'found.in': 'parent',
+              },
+            },
+          },
+        },
+      };
+
+      // @ts-expect-error Calling private member
+      boundary._onTouchStart(event);
+
+      expect(mockSpan.setAttributes).toHaveBeenCalledWith({
+        'found.in': 'parent',
+      });
+    });
+
+    it('does not call setAttributes when no span is created', () => {
+      const { defaultProps } = TouchEventBoundary;
+      const boundary = new TouchEventBoundary(defaultProps);
+
+      jest.spyOn(userInteractionModule, 'startUserInteractionSpan').mockReturnValue(undefined);
+
+      const event = {
+        _targetInst: {
+          elementType: { displayName: 'Button' },
+          memoizedProps: {
+            'sentry-label': 'test',
+            'sentry-span-attributes': {
+              'custom.key': 'value',
+            },
+          },
+        },
+      };
+
+      // @ts-expect-error Calling private member
+      expect(() => boundary._onTouchStart(event)).not.toThrow();
+    });
+  });
 });
diff --git a/samples/react-native/e2e/captureSpaceflightNewsScreenTransaction.test.ts b/samples/react-native/e2e/captureSpaceflightNewsScreenTransaction.test.ts
index 2bdd30486e..6e9d6be8b5 100644
--- a/samples/react-native/e2e/captureSpaceflightNewsScreenTransaction.test.ts
+++ b/samples/react-native/e2e/captureSpaceflightNewsScreenTransaction.test.ts
@@ -55,12 +55,19 @@ describe('Capture Spaceflight News Screen Transaction', () => {
     expect(first![1].timestamp!).toBeLessThan(second![1].timestamp!);
   });
 
-  it('all transaction envelopes have time to display measurements', async () => {
-    allTransactionEnvelopes.forEach(envelope => {
-      expectToContainTimeToDisplayMeasurements(
-        getItemOfTypeFrom<EventItem>(envelope, 'transaction'),
-      );
-    });
+  it('all navigation transaction envelopes have time to display measurements', async () => {
+    allTransactionEnvelopes
+      .filter(envelope => {
+        const item = getItemOfTypeFrom<EventItem>(envelope, 'transaction');
+        // Only check navigation transactions, not user interaction transactions
+        // User interaction transactions (ui.action.touch) don't have time-to-display measurements
+        return item?.[1]?.contexts?.trace?.op !== 'ui.action.touch';
+      })
+      .forEach(envelope => {
+        expectToContainTimeToDisplayMeasurements(
+          getItemOfTypeFrom<EventItem>(envelope, 'transaction'),
+        );
+      });
   });
 
   function expectToContainTimeToDisplayMeasurements(
diff --git a/samples/react-native/src/Screens/SpaceflightNewsScreen.tsx b/samples/react-native/src/Screens/SpaceflightNewsScreen.tsx
index f03f9b76fb..e7830d2aa3 100644
--- a/samples/react-native/src/Screens/SpaceflightNewsScreen.tsx
+++ b/samples/react-native/src/Screens/SpaceflightNewsScreen.tsx
@@ -106,6 +106,13 @@ export default function NewsScreen() {
     }
     return (
       <Pressable
+        sentry-label="load-more-articles"
+        sentry-span-attributes={{
+          'articles.loaded': articles.length,
+          'pagination.page': page,
+          'pagination.next_page': page + 1,
+          'auto_load.count': autoLoadCount,
+        }}
         style={({ pressed }) => [
           styles.loadMoreButton,
           pressed && styles.loadMoreButtonPressed,